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Replacement of therapy by an antiretroviral regimen not containing indinavir, while retaining other protease inhibitors and lamivudine, resolves retinoid-like manifestations without recurrences.
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Sapropterin moderate caution is advised with the concomitant use of sapropterin and indinavir as coadministration may result in increased systemic exposure of indinavir.
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However, amprenavir-resistant isolates were susceptible to either indinavir or saquinavir.
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Long-term efficacy, safety, and tolerability of indinavir-based therapy in protease inhibitor-na ve adults with advanced hiv infection.
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